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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Aluminum Hydroxide
supplement:
Citric Acid
Research Papers that Mention the Interaction
“Although no evidence of maternal and embryo/fetal toxicity was observed when high doses of aluminum hydroxide were given orally to pregnant rats and mice during organogenesis, signs of maternal and developmental toxicity were found in mice when aluminum hydroxide was given concurrently with citric or lactic acids.”
Reproductive and developmental toxicity of aluminum: a review.“ Citric acid did not significantly affect the antacid-induced PGE2 release except in combination with a low dose of aluminium hydroxide , with which a significant increase was seen.”
Gastric prostaglandin E2 release induced by aluminium hydroxide and aluminium hydroxide-containing antacids in rats. Effect of low doses and citric acid.“In terms of CA, a more striking negative effect on the growth ability of the flocs was observed compared to P. The strong complexing/coordination interactions between CA and aluminum hydroxide is the main reason behind the influence.”
The influence of various additives on coagulation process at different dosing point: From a perspective of structure properties.“ Citric acid has been shown to act as an agent for increasing the solubility of aluminum oxyhydroxides in aqueous solutions of high (>2.47 mol/mol) hydroxide-to-aluminum ratios.”
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