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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Alprostadil
supplement:
Linoleic Acid
Research Papers that Mention the Interaction
“ PGE1 biosynthesis is enhanced by the essential fatty acid, linoleic acid , by the platelet aggregating agent thromboxane (TX) A2, by cholesterol and by melatonin.”
A new concept of lifestyle-related cardiovascular disease: the importance of interactions between cholesterol, essential fatty acids, prostaglandin E1 and thromboxane A2.“The "rat aorta-loop" model proved to … to about 200 h. A constant intravenous PGE1 infusion of 10 mug/h increased OT significantly from the control value of 126.6 h … - a significant decrease in platelet stickiness was found in a group of patients consuming 12 cal% linoleic acid ….”
“These data support the hypothesis that part of the excess of dietary linoleic acid can lead to increased PGE1 concentrations.”
The effects of linoleic acid and prostaglandin E1 on arterial thrombosis.
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