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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Alprostadil and Linoleic Acid


Linoleic Acid

Research Papers that Mention the Interaction

PGE1 biosynthesis is enhanced by the essential fatty acid, linoleic acid , by the platelet aggregating agent thromboxane (TX) A2, by cholesterol and by melatonin.
Medical hypotheses  •  1980  |  View Paper
The "rat aorta-loop" model proved to … to about 200 h. A constant intravenous PGE1 infusion of 10 mug/h increased OT significantly from the control value of 126.6 h … - a significant decrease in platelet stickiness was found in a group of patients consuming 12 cal% linoleic acid ….
These data support the hypothesis that part of the excess of dietary linoleic acid can lead to increased PGE1 concentrations.
Acta biologica et medica Germanica  •  1976  |  View Paper