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Possible Interaction: Alprostadil and Epinephrine

supplement:

Epinephrine

Research Papers that Mention the Interaction

Pretreatment of the PRP with epinephrine increased the maximum transmittance during ADP aggregation, produced less-reversible aggregates (less subject to deaggregation by PGE1 ), and increased the aggregate flow resistance over the range of filtration pressures tested.
Thrombosis research  •  1987  |  View Paper
Prostaglandin E1 PGE1 ) exerted an immediate inhibitory effect upon the induction of platelet aggregation by adenosinediphosphate, epinephrine , thrombin, bovine fibrinogen, or sodium fluoride, whereas dibutyryl cyclic adenosinemonophosphate (DBcAMP) produced a delayed type of inhibition of aggregation induced by these same agents.
American journal of clinical pathology  •  1977  |  View Paper
Prostaglandin E1 , which stimulates adenylate cyclase to form cAMP, inhibited the antibody effects 50% at 50-fold the concentration required for equivalent inhibition of aggregation and release by epinephrine.
Blood  •  1977  |  View Paper
PGE1 potentiates contractions caused by other agents such as epinephrine.
Fertility and sterility  •  1977  |  View Paper
Preincubation of macrophages with prostaglandin E1 greatly reduced the subsequent responses of cAMP generation to prostaglandin E1 and unexpectedly also to epinephrine.
Archives of biochemistry and biophysics  •  1986  |  View Paper
The cholinergic agonist carbachol, epinephrine , and the opiate morphine all inhibit prostaglandin E1 (PGE1)-stimulated adenylate cyclase in homogenates from the neuroblastoma-glioma hybrid NG108-15.
Journal of neurochemistry  •  1982  |  View Paper
PGE1 at 1 microM caused a sharp increase in cAMP and complete inhibition of platelet aggregation induced by AA plus EPI.
Thrombosis research  •  1982  |  View Paper
PGE1 alone had no significant effect, but in combination with epinephrine it abolished the inhibitory action of the catecholamine in both groups.
Nutrition and metabolism  •  1975  |  View Paper
Epi also partially reversed the increase in cAMP level produced by prostaglandin E1.
The American journal of physiology  •  1975  |  View Paper
Responses to combinations of epinephrine and PGE1 were additive.
Journal of cyclic nucleotide research  •  1975  |  View Paper
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