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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Alprostadil
supplement:
Capsaicin
Research Papers that Mention the Interaction
“Responses evoked by bradykinin, capsaicin or submaximal thermal stimulation were enhanced in the presence of prostaglandin E1 , prostaglandin E2, prostaglandin F2 alpha, prostaglandin I2 and the stable prostaglandin I2 analogue cicaprost, but not by prostaglandin D2.”
Sensitization of peripheral afferent fibres in the in vitro neonatal rat spinal cord-tail by bradykinin and prostaglandins“ PGE1 (1-1000 micrograms/kg) inhibited the leakage induced by capsaicin in the trachea and bronchi concentration dependently with complete inhibition at a concentration of 1000 micrograms/kg.”
“2 In rats pretreated … of 50 mg capsaicin over 4 days, the …, formalin, HCl, KCl, prostaglandin E1 , bradykinin and bradykinin with prostaglandin E1 (10−6 m) were greatly reduced, the responses to histamine … were slightly reduced and those to adenosine 5′‐triphosphate (ATP) and compound 48/80 were unaffected.”
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