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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Alprostadil and Adrenocorticotropic Hormone

Research Papers that Mention the Interaction

Infusion of PGE1 , PGE2 or PGF2 alpha (1 and/or 5 micrograms infused intracerebroventricularly) stimulated ACTH secretion.
Neuroendocrinology  •  1997  |  View Paper
The addition of ACTH and PGE1 resulted in inhibition of aldosterone secretion when compared with that obtained by ACTH alone.
Masui. The Japanese journal of anesthesiology  •  1991  |  View Paper
Submaximal or maximal concentrations of ACTH and PGE-2 given simultaneously elicited a response which was no greater than that obtained with either stimulant alone.
Prostaglandins  •  1975  |  View Paper
Excessive amounts of PGE1 only partially inhibited the lipolytic effect of even submaximal concentrations of epinephrine, glucagon, and ACTH in adipocytes, although total inhibitions were obtainable with appropriate concentrations of the β-adrenergic blocking compounds.
While PGE1 , Ko 592, and propranolol all inhibited the stimulatory effects of glucagon and ACTH on lipolysis in adipocytes, neither agent influenced the action of either hormone on glucose oxidation; the latter finding suggests that β-receptors do not mediate the stimulatory effects of these hormones on glucose oxidation.
The Journal of biological chemistry  •  1969  |  View Paper