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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Alprenolol
supplement:
Epinephrine
Research Papers that Mention the Interaction
“The inhibitory effect of adrenaline is reversed by preincubating the cells with a beta-blocker, alprenolol , but not by preincubating them with an alpha-blocker, phentolamine.”
Inhibition of cholinergic histamine release in rat mast cells“ Alprenolol triggered a dose-dependent hypothermia that was reversed by low doses of epinephrine and ephedrine.”
“The beta-adrenergic antagonist L-alprenolol , in doses that did not influence basal adenylate cyclase activity, produced a dose-related inhibition of the stimulatory effect of T3 and of the effects of epinephrine and isoproterenol as well.”
“Propranolol and alprenolol inhibited the effect of adrenaline , but phenoxybenzamine and phentolamine did not inhibit the effect.”
“Prior or simultaneous addition of L-alprenolol (10 microM), which, we have previously shown, blocks the effect of both T3 and epinephrine on 2-DG uptake, also blocked the increase in thymocyte cAMP concentration induced by these agents.”
“The adrenergic beta-receptor blockers: Propranolol, Alprenolol , Oxprenolol, Pindolol, Practolol, and Talinolol, inhibit the calorigenic action of adrenaline in experiments on rats.”
“As previously demonstrated, T(3) increased 2-DG accumulation, and like epinephrine , its effect was blocked by alprenolol.”
“The response to epinephrine was inhibited by the beta-antagonist, alprenolol , but the alpha-antagonist, phentolamine, had no effect.”
“Blood glucose levels were enhanced in these conditions, but were unaffected in rats treated with epinephrine plus alprenolol.”
“Chronic administration of epinephrine to adult male rats resulted in a significant increase in the rate of ethanol elimination, when given alone or together with the beta-adrenergic blocker alprenolol.”
“The alpha-adrenergic antagonist phentolamine has no effect on the adenylate cyclase activation by catecholamines, glucagon and histamine; the beta-adrenergic antagonist alprenolol competitively inhibits the effects of isoproterenol, epinephrine and norepinephrine, having no effect on the enzyme activation by glucagon and histamine.”
“It is evident that both MK 950 and alprenolol , like oxprenolol, can unmask excitatory responses in intestinal smooth muscle exposed to adrenaline.”
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