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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
drug:
Alprazolam
supplement:
St John's Wort
Research Papers that Mention the Interaction
“Since then, subsequent research has shown that SJW altered the pharmacokinetics of drugs such as digoxin, tacrolimus, indinavir, warfarin, alprazolam , simvastatin, or oral contraceptives.”
Clinical relevance of St. John's wort drug interactions revisited“Clinical trials indicate …’s wort Hypericum perforatum ), via cytochrome P450 (CYP) and/or P-glycoprotein … plasma concentrations (and/or increases the clearance) of alprazolam , amitriptyline, atorvastatin, chlorzoxazone, ciclosporin, debrisoquine, digoxin, erythromycin, fexofenadine, gliclazide, imatinib, indinavir, irinotecan, ivabradine, …, nifedipine, omeprazole, oral contraceptives, quazepam, simvastatin, tacrolimus, talinolol, verapamil, voriconazole and warfarin.”
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