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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Alprazolam and St John's Wort


St John's Wort

Research Papers that Mention the Interaction

Since then, subsequent research has shown that SJW altered the pharmacokinetics of drugs such as digoxin, tacrolimus, indinavir, warfarin, alprazolam , simvastatin, or oral contraceptives.
British journal of pharmacology  •  2019  |  View Paper
Clinical trials indicate …’s wort Hypericum perforatum ), via cytochrome P450 (CYP) and/or P-glycoprotein … plasma concentrations (and/or increases the clearance) of alprazolam , amitriptyline, atorvastatin, chlorzoxazone, ciclosporin, debrisoquine, digoxin, erythromycin, fexofenadine, gliclazide, imatinib, indinavir, irinotecan, ivabradine, …, nifedipine, omeprazole, oral contraceptives, quazepam, simvastatin, tacrolimus, talinolol, verapamil, voriconazole and warfarin.
Drugs  •  2012  |  View Paper