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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Alprazolam and Melatonin

supplement:

Melatonin

Research Papers that Mention the Interaction

Addition of melatonin to alprazolam had superior anxiolysis compared with either drugs alone or placebo.
BioMed research international  •  2014  |  View Paper
Melatonin concentrations were … suppressed by alprazolam at 23:00, midnight, 01:00, 06:00, and 07:00 h. A trend toward suppression was evident from 02:00 to 05:00 h. Cortisol concentrations were also suppressed by alprazolam at several times throughout the night (01:00-04:00 h).
Chronobiology international  •  1993  |  View Paper