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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Alprazolam
supplement:
Melatonin
Research Papers that Mention the Interaction
“Addition of melatonin to alprazolam had superior anxiolysis compared with either drugs alone or placebo.”
Premedication with Oral Alprazolam and Melatonin Combination: A Comparison with Either Alone—A Randomized Controlled Factorial Trial“ Melatonin concentrations were … suppressed by alprazolam at 23:00, midnight, 01:00, 06:00, and 07:00 h. A trend toward suppression was evident from 02:00 to 05:00 h. Cortisol concentrations were also suppressed by alprazolam at several times throughout the night (01:00-04:00 h).”
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