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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Alprazolam and Kava



Research Papers that Mention the Interaction

Piper methysticum (kava) alters or enhances the effects of levodopa and alprazolam.
Journal of the National Cancer Institute  •  2002  |  View Paper
Kava (Piper methysticum) increases 'off' periods in Parkinson patients taking levodopa and can cause a semicomatose state when given concomitantly with alprazolam.
Drugs  •  2001  |  View Paper
In one case, a combination of kava kava and Xanax landed a man in the hospital in a coma-like condition.
Perspectives in psychiatric care  •  2000  |  View Paper
Kava when used with alprazolam has resulted in coma.
Archives of internal medicine  •  1998  |  View Paper
We believe that these findings may explain the mechanism governing the possible interaction between kava and alprazolam.
We report an interaction between kava and alprazolam that caused a semicomatose state.
Annals of Internal Medicine  •  1996  |  View Paper