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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Alprazolam
supplement:
Epinephrine
Research Papers that Mention the Interaction
“Compared to placebo, alprazolam significantly increased subjective sedation, reduced plasma adrenaline and noradrenaline concentrations and mean blood pressure (MBP) during supine rest, and attenuated plasma adrenaline responses during the CWT and the OCT; these effects during the CWT and OCT appeared to be dose-dependent.”
Effects of alprazolam and lorazepam on catecholaminergic and cardiovascular activity during supine rest, mental load and orthostatic challenge“ Alprazolam significantly attenuated the 2DG-induced increases in plasma ACTH and epinephrine , but did not significantly effect plasma norepinephrine and DHPG.”
“At baseline, intravenous alprazolam administration caused acute reductions in whole-brin CBF (25% to 30% decrease), memory, plasma epinephrine , and self-rated alertness.”
“Furthermore, chronic alprazolam decreased basal activity of the hypothalamic–pituitary– adrenal axis , CRF mRNA expression in the central nucleus of the amygdala, and CRF1 mRNA expression and receptor binding in the basolateral amygdala.”
Chronic Administration of the Triazolobenzodiazepine Alprazolam Produces Opposite Effects on Corticotropin-Releasing Factor and Urocortin Neuronal Systems
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