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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Alprazolam and Epinephrine



Research Papers that Mention the Interaction

Compared to placebo, alprazolam significantly increased subjective sedation, reduced plasma adrenaline and noradrenaline concentrations and mean blood pressure (MBP) during supine rest, and attenuated plasma adrenaline responses during the CWT and the OCT; these effects during the CWT and OCT appeared to be dose-dependent.
Psychopharmacology  •  1996  |  View Paper
Alprazolam significantly attenuated the 2DG-induced increases in plasma ACTH and epinephrine , but did not significantly effect plasma norepinephrine and DHPG.
Biological Psychiatry  •  1992  |  View Paper
At baseline, intravenous alprazolam administration caused acute reductions in whole-brin CBF (25% to 30% decrease), memory, plasma epinephrine , and self-rated alertness.
Neuropsychopharmacology  •  1993  |  View Paper
Furthermore, chronic alprazolam decreased basal activity of the hypothalamic–pituitary– adrenal axis , CRF mRNA expression in the central nucleus of the amygdala, and CRF1 mRNA expression and receptor binding in the basolateral amygdala.
The Journal of Neuroscience  •  2000  |  View Paper