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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Alprazolam and Dehydroepiandrosterone

Research Papers that Mention the Interaction

DHEA and APZ in combination significantly increased the GH response to exercise (P < 0.01).
Together DHEA and APZ may up-regulate GH during exercise by blunting a suppressive (HPA axis) and potentiating an excitatory (glutamate receptor) system.
The Journal of clinical endocrinology and metabolism  •  2005  |  View Paper
Alprazolam produced (1) significant increases in DHEA concentrations at 7 hours in both young and elderly men; (2) significant decreases in cortisol concentrations; and (3) no change in DHEA-S concentrations.
These results suggest that alprazolam modulates peripheral concentrations of DHEA and that DHEA and/or DHEA-S may have an in vivo role in modulating GABA receptor-mediated responses.
Journal of clinical psychopharmacology  •  1999  |  View Paper