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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Alpha-Tocopherol Succinate
drug:
Aldesleukin
Research Papers that Mention the Interaction
“OBJECTIVE We previously demonstrated that a high dose of alpha-tocopheryl succinate inhibits interleukin-2 (IL-2) mRNA and production in autoimmune-prone MRL/lpr mice.”
Low and high levels of alpha-tocopherol exert opposite effects on IL-2 possibly through the modulation of PPAR-gamma, IkappaBalpha, and apoptotic pathway in activated splenocytes.
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