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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Alpha-lipoic acid
supplement:
Vitamin C
Research Papers that Mention the Interaction
“NO-mediated vasodilation was improved by ascorbic acid at 10 mM, but not 1 mM. Improvements of endothelial function by ascorbic acid and lipoic acid were closely related.”
Beneficial effects of alpha-lipoic acid and ascorbic acid on endothelium-dependent, nitric oxide-mediated vasodilation in diabetic patients: relation to parameters of oxidative stress.“When administered together with ascorbic acid, lipoic acid changes the characteristic heavy to light chain ratio of ferritin makeup.”
Alpha lipoic acid changes iron uptake and storage in lens epithelial cells.“Result A decrease in the level of oxidative stress was observed among those supplemented with either alpha lipoic acid alone or along with vitamin C , with a slightly more decrease in oxidative stress in the latter group.”
“The percentage of the benefit of treatment on supplementation with vitamin C and alpha lipoic acid showed a marked increase in group V (26.9%) cases after supplementation with both in combination.”
The effect of antioxidants in acute amitriptyline poisoning“ Lipoic acid quenches reactive oxygen species, chelates metal ions, and reduces the oxidized forms of other antioxidants such as vitamin C , vitamin E, and glutathione.”
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