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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Alpha-lipoic acid and Paclitaxel

Research Papers that Mention the Interaction

Importantly, the α-lipoic acid had to be administered prior to exposure to cisplatin or paclitaxel in order to prevent neurotoxicity.
In contrast to the data with cisplatin, the effect of α-lipoic acid on paclitaxel induced apoptosis was less significant, which is not surprising as apoptosis is not the main toxic mechanism of paclitaxel.
Experimental Neurology  •  2009  |  View Paper
Lipoic acid and paclitaxel in combination obviously strengthened their individual inhibitory effects on tumor cells (P < 0.05).
Genetics and molecular research : GMR  •  2015  |  View Paper