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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Alpha-lipoic acid and Naloxone

Research Papers that Mention the Interaction

In animals injected with morphine plus naloxone , which show altered pain thresholds, high fecal excretion and jumping behaviour, treatment with alpha-lipoic acid increases latency times, decreases fecal excretion and reduces jumping.
The administration of alpha-lipoic acid is demonstrated to control the alterations in plasma glucose levels, peroxide values or behavioural profile in animals receiving morphine or morphine plus naloxone.
The injection of alpha-lipoic acid decreases glycemia in rats treated with morphine or morphine plus naloxone.
Arzneimittel-Forschung  •  2009  |  View Paper
The administration of LA lowered MDA levels in the rats treated with morphine or morphine plus naloxone , and also decreased MDA values and abstinence signs in the animals treated with morphine plus naloxone.
Fundamental & clinical pharmacology  •  2008  |  View Paper