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Discover Supplement-Drug Interactions
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Last Updated: 5 years ago
supplement:
Alpha-lipoic acid
drug:
Methotrexate
Research Papers that Mention the Interaction
“Conclusions: Oxidative damage of MTX in rat lung is partially reduced when combined with ALA.”
Protective Effects of Alpha-Lipoic Acid on Methotrexate-Induced Oxidative Lung Injury in Rats“On the other hand, ALA treatment reversed all these biochemical indices as well as histopathological alterations induced by MTX.”
Does alfa lipoic acid prevent liver from methotrexate induced oxidative injury in rats?“In conclusion, it can be stated that, although ALA is more effective in preventing the toxic effects of MTX on the liver and kidney, PTX also has a preventive effect.”
“ ALA treatment reversed all biochemical indices as well as histopathological alterations induced by MTX administration.”
“These findings suggest that co-administration of LA with MTX is associated with reduction in oxidative injury and tissue damage in the intestine.”
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