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Discover Supplement-Drug Interactions

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Last Updated: a month ago

Possible Interaction: Alpha-lipoic acid and Methotrexate

Research Papers that Mention the Interaction

CONCLUSIONS Oxidative damage of MTX in rat lung is partially reduced when combined with ALA.
CONCLUSIONS Oxidative damage of MTX in rat lung is partially reduced when combined with ALA.
Journal of investigative surgery : the official journal of the Academy of Surgical Research  •  2018  |  View Paper
On the other hand, ALA treatment reversed all these biochemical indices as well as histopathological alterations induced by MTX.
Acta cirurgica brasileira  •  2015  |  View Paper
In conclusion, it can be stated that, although ALA is more effective in preventing the toxic effects of MTX on the liver and kidney, PTX also has a preventive effect.
Environmental toxicology and pharmacology  •  2015  |  View Paper
ALA treatment reversed all biochemical indices as well as histopathological alterations induced by MTX administration.
ALA treatment reversed all biochemical indices as well as histopathological alterations induced by MTX administration.
European review for medical and pharmacological sciences  •  2015  |  View Paper
These findings suggest that co-administration of LA with MTX is associated with reduction in oxidative injury and tissue damage in the intestine.
Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology  •  2011  |  View Paper