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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Alpha-lipoic acid
drug:
Leptin
Research Papers that Mention the Interaction
“Treatment of 3T3-L1 adipocytes with LA caused a concentration-dependent inhibition of leptin secretion and gene expression.”
Lipoic acid inhibits leptin secretion and Sp1 activity in adipocytes.“ LA treatment induced a significant decrease in glucose, TG, and total cholesterol levels and significantly increased serum insulin and leptin levels in comparison with the diabetic group.”
“In addition, lipoic acid dose-dependently lowered serum concentrations of insulin and leptin , but increased those of adiponectin.”
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