Possible Interaction: Alpha-lipoic acid and 3-Nitrotyrosine

“Similarly, alpha-lipoic acid attenuates the formation and collection of nitrotyrosine in retinal cells and thereby decreases the visual deterioration in retinopathies such as diabetic retinopathy5.”

“In addition, the inflammatory responses including elevation of superoxide formation, myeloperoxidase activity, polymorphonuclear neutrophils infiltration, nitrotyrosine , inducible nitric oxide synthase expression and nuclear factor-kappa B (NF-κB) activation in lung tissues of LPS-instilled rats were also markedly reduced by ALA.”