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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Alpha-Ketoglutaric Acid and Vitamin B 6

Research Papers that Mention the Interaction

The affinity (Km)of the albumin-PLP complex for apoGOT was 1.56μM. Simultaneous addition of α-ketoglutarate to the preincubation mixture decreased markedly the transfer of PLP.
Journal of nutritional science and vitaminology  •  1973  |  View Paper
Pyridoxal phosphate activates the soluble form of tyrosine transminase over 4-fold and α-ketoglutarate over 2-fold; α-ketoglutarate increases too the degree of conjugation of the enzyme with the coenzyme.
Biochimica et biophysica acta  •  1971  |  View Paper