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“The inhibitory effects of alpha 2-adrenergic agonists on forskolin-stimulated cAMP production were specifically blocked when they were combined with the alpha 2-adrenergic antagonist yohimbine.”
Japanese journal of pharmacology • 1995 | View Paper
“In the presence of alpha 2-adrenergic blockade by yohimbine , NPY, PYY, and PP (IV) increased intraluminal pressure of the colon +4.2, +2.9, and +2.5 mmHg compared to saline baseline.”