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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Allyl Isothiocyanate
drug:
Oxaliplatin
Research Papers that Mention the Interaction
“The nocifensive behaviors evoked by intraplantar injections of allyl-isothiocyanate (AITC; TRPA1 agonist) were significantly enhanced in mice treated for 2 h with oxaliplatin (1–10 mg/kg) in a dose-dependent manner, while capsaicin (TRPV1 agonist)-evoked nocifensive behaviors were not affected.”
Acute cold hypersensitivity characteristically induced by oxaliplatin is caused by the enhanced responsiveness of TRPA1 in mice
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