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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Allyl Isothiocyanate and Calcium Supplement

Research Papers that Mention the Interaction

TRPA1-specific activator namely allyl isothiocyanate AITC ) increases intracellular calcium ion (Ca2+) levels while two different inhibitors namely A-967079 as well as HC-030031 reduce intracellular Ca2+ levels in T cells; TRPA1 inhibition also reduces TCR-mediated calcium influx.
Bioscience reports  •  2019  |  View Paper
AITC elicited an intracellular calcium increase that was not dependent on phorpholipase C(β)₂ (PLC(β)₂) activation but was dependent on extracellular calcium concentration.
Assay and drug development technologies  •  2010  |  View Paper
Stimulation of SCLC cells with AITC led to a rise of the intracellular calcium concentration.
Biochemical pharmacology  •  2013  |  View Paper
AITC suppressed the intracellular calcium level in the phorbol myristate acetate (PMA) plus calcium ionophore A23187-stimulated human mast cell line.
International immunopharmacology  •  2011  |  View Paper