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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Allyl Isothiocyanate
supplement:
Calcium Supplement
Research Papers that Mention the Interaction
“TRPA1-specific activator namely allyl isothiocyanate AITC ) increases intracellular calcium ion (Ca2+) levels while two different inhibitors namely A-967079 as well as HC-030031 reduce intracellular Ca2+ levels in T cells; TRPA1 inhibition also reduces TCR-mediated calcium influx.”
Transient receptor potential ankyrin1 channel is endogenously expressed in T cells and is involved in immune functions“ AITC elicited an intracellular calcium increase that was not dependent on phorpholipase C(β)₂ (PLC(β)₂) activation but was dependent on extracellular calcium concentration.”
“Stimulation of SCLC cells with AITC led to a rise of the intracellular calcium concentration.”
“ AITC suppressed the intracellular calcium level in the phorbol myristate acetate (PMA) plus calcium ionophore A23187-stimulated human mast cell line.”
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