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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Allopurinol and Vitamin E


Vitamin E

Research Papers that Mention the Interaction

Although, there was a significant decrease in … values of apoptosis in animals receiving vitamine E (8.7%–….3%) and allopurinol (18.4%–13.5%) (P<0.05), animals on verapamil, MgOH and potassium citrate medication … an increase in these values or the change was not found to be significant.
Urological Research  •  2003  |  View Paper
As allopurinol , a xanthine oxidase inhibitor, prevents the decrease in alpha-tocopherol , xanthine oxidase may contribute to this oxidative stress.
Alcohol and alcoholism (Oxford, Oxfordshire). Supplement  •  1987  |  View Paper
Conclusions Allopurinol synergistically increases the protective effect of metformin and vitamin E in treatment of NAFLD, namely via reduction of uric acid synthesis and iNOS expression.
Results Combination of allopurinol plus metformin plus vitamin E significantly attenuated fatty changes compared to their respective monotherapy.
Clinical and experimental hepatology  •  2019  |  View Paper