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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Allopurinol and Vitamin C


Vitamin C

Research Papers that Mention the Interaction

One trial including 40 participants, at moderate to high risk of bias, compared vitamin C alone with allopurinol and with allopurinol plus vitamin C in a three-arm trial.
The Cochrane database of systematic reviews  •  2014  |  View Paper
The reduction in SU level over 8 … was significantly less in those patients receiving vitamin C compared to those who started or increased the dose of allopurinol (mean reduction 0.014 mmoles/liter [0.23 mg/dl] versus 0.118 mmoles/liter [1.9 mg/dl]; P < 0.001).
Arthritis and rheumatism  •  2013  |  View Paper
The binding reaction was not inhibited by superoxide dismutase or allopurinol , but was strongly inhibited by ascorbic acid and glutathione.
Acta pharmacologica et toxicologica  •  1977  |  View Paper