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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Allopurinol and Thiamine Pyrophosphate

Research Papers that Mention the Interaction

This is consistent with the … that the intracellular concentrations of TPP and TPPR-MP are sufficient … inhibit the conversion of allopurinol to allopurinol ribonucleotide (HPPR-MP) by the hypoxanthine-guanine phosphoribosyltransferase by 30 per cent and the amination of HPPR-MP by adenylosuccinate synthetase by 50 per cent respectively.
Biochemical pharmacology  •  1982  |  View Paper