supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 years ago
drug:
Allopurinol
supplement:
Thiamine Pyrophosphate
Research Papers that Mention the Interaction
“This is consistent with the … that the intracellular concentrations of TPP and TPPR-MP are sufficient … inhibit the conversion of allopurinol to allopurinol ribonucleotide (HPPR-MP) by the hypoxanthine-guanine phosphoribosyltransferase by 30 per cent and the amination of HPPR-MP by adenylosuccinate synthetase by 50 per cent respectively.”
Antileishmanial action of 4-thiopyrazolo (3.4-d) pyrimidine and its ribonucleoside. Biological effects and metabolism.
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback