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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Allopurinol
supplement:
Glucose
Research Papers that Mention the Interaction
“Additionally, through its inhibition of both IL-1β and ROS production by the trophoblast, allopurinol reduced the additional pro-inflammatory and anti-angiogenic responses to excess glucose.”
“ Allopurinol also significantly inhibited excess glucose induced trophoblast secretion of anti-angiogenic sFlt-1.”
“Together, our findings indicate that the xanthine oxidase inhibitor allopurinol inhibited excess glucose induced trophoblast IL-1β secretion.”
Allopurinol inhibits excess glucose-induced trophoblast IL-1b and ROS production.“ Allopurinol improved left ventricular pressure from 38 ± 7% to 55 ± 9% (p < 0.002) in the presence of glucose and from 8 ± 3% to 27 ± 6.3% (p < 0.001) in the absence of glucose.”
Allopurinol Enhances Adenine Nucleotide Levels and Improves Myocardial Function in Isolated Hypoxic Rat Heart“Also, allopurinol inhibits the second phase of O2 uptake and glucose release characteristic of concentrations of AGEPC or increased [K+]o equal to or greater than their reported half-maximal concentration for glucose release.”
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