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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Allopurinol and Glucose



Research Papers that Mention the Interaction

Additionally, through its inhibition of both IL-1β and ROS production by the trophoblast, allopurinol reduced the additional pro-inflammatory and anti-angiogenic responses to excess glucose.
Allopurinol also significantly inhibited excess glucose induced trophoblast secretion of anti-angiogenic sFlt-1.
Together, our findings indicate that the xanthine oxidase inhibitor allopurinol inhibited excess glucose induced trophoblast IL-1β secretion.
Reproduction  •  2019  |  View Paper
Allopurinol improved left ventricular pressure from 38 ± 7% to 55 ± 9% (p < 0.002) in the presence of glucose and from 8 ± 3% to 27 ± 6.3% (p < 0.001) in the absence of glucose.
Biochemistry (Moscow)  •  2004  |  View Paper
Also, allopurinol inhibits the second phase of O2 uptake and glucose release characteristic of concentrations of AGEPC or increased [K+]o equal to or greater than their reported half-maximal concentration for glucose release.
The Biochemical journal  •  1987  |  View Paper