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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Allopurinol
supplement:
Arginine
Research Papers that Mention the Interaction
“In summary, combined supplementation with allopurinol and l-arginine might be very effective in osteoarthritis.”
“The combined supplementation with allopurinol and l-arginine increased catalase, SOD, GSH, and Gpx, while it decreased lipid peroxidation, IL-6, IL-1β, and TNF-α.”
“While TNF-α, IL-6, IL-1β, and NF-κB mRNA and protein expression were higher in control HOb-OA cells, the combined supplementation with allopurinol and l-arginine substantially reduced their expression in HOb-OA cells by >40%.”
l-Arginine and allopurinol supplementation attenuates inflammatory mediators in human osteoblasts-osteoarthritis cells.“ Arginine transport was significantly decreased in control rats treated with allopurinol.”
Hyperuricemia Attenuates Aortic Nitric Oxide Generation, through Inhibition of Arginine Transport, in Rats
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