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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Allopurinol
supplement:
Arachidonic Acid
Research Papers that Mention the Interaction
“Sensitization by hypoxia to AA is blocked by allopurinol , which inhibits the formation of uric acid.”
In vitro and in vivo arachidonic acid conversions into biologically active derivatives are enhanced by uric acid.“The pretreatment of allopurinol , an xanthine oxidase inhibitor, diminished the trans isomer of arachidonic acid-induced increase in the 2',7'-dichlorofluorescein-fluorescence intensity, indicating the role of xanthine dehydrogenase/xanthine oxidase in mediating trans isomer of arachidonic acid-induced reactive oxygen species generation.”
All-trans Arachidonic acid generates reactive oxygen species via xanthine dehydrogenase/xanthine oxidase interconversion in the rat liver cytosol in vitro
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