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Last Updated: 2 years ago

Possible Interaction: Alkaline Phosphatase and Vitamin B 6

Research Papers that Mention the Interaction

A significant negative linear relationship was found between the log PLP and log ALP (log PLP = 5.99-2.76 log ALP; r = -0.85, P < 0.001).
Clinical science  •  1998  |  View Paper
Biochemically, the reduction in ALP activity is associated with alterations in the extracellular metabolism of various phosphorylated compounds, including inorganic pyrophosphate (PPi), phosphoethanolamine, and pyridoxal 5'-phosphate.
Critical reviews in clinical laboratory sciences  •  1991  |  View Paper
PLP is known to be hydrolyzed to pyridoxal (PL) by alkaline phosphatase (ALP), resulting in an inverse relationship between PLP and ALP.
The Journal of nutrition  •  1987  |  View Paper
Plasma pyridoxal-5′-phosphate (PLP), which significantly increased (61%) in these same rats, was negatively correlated (r=−0.74,P<0.02) with plasma alkaline phosphatase activity.
Biological Trace Element Research  •  2007  |  View Paper
This change was accompanied by a slight increase of Pi A negative correlation was found between plasma AP and PLP.
International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition  •  1988  |  View Paper
This GWAS of B6 vitamers identifies alkaline phosphatase as a key regulator in human vitamin B6 metabolism in CSF as well as plasma.
Genes  •  2018  |  View Paper
Alkaline phosphatase catalyzes the hydrolysis of pyridoxal phosphate to generate pyridoxal, restoring the fluorescence of BSA-AuNCs.
Biosensors & bioelectronics  •  2017  |  View Paper