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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Alkaline Phosphatase
supplement:
Ubiquinone
Research Papers that Mention the Interaction
“Findings indicated that coenzyme Q10 decreased the plasma levels in alkaline phosphatase , alanine aminotransferase, and aspartate aminotransferase in the cecal ligation and puncture group.”
Protective Role of Coenzyme Q10 in Acute Sepsis-Induced Liver Injury in BALB/c Mice“The plasma levels of glucose, cholesterol and alkaline phosphatase ALP ) activity were quadratically decreased by increased levels of CoQ10.”
“ CoQ10 treatments increased the activities of antioxidant enzymes (superoxide dismutase, GPx, catalase, glutathione S-transferase), protease inhibitors, biomarkers (aspartate aminotransferase, alkaline phosphatase , alanine aminotransferase), the total antioxidant potential level, and concentrations of uric acid and creatinine.”
“In bone formation study, CoQ10 acted to enhance the induction of osteoblastogenic biomarkers including alkaline phosphatase , type 1 collagen, bone sialoprotein, osteoblast-specific transcription factor Osterix, and Runt-related transcription factor 2 and, also promoted matrix mineralization by enhancing bone nodule formation in a dose-dependent manner.”
“ Ubiquinol-1 in aerated aqueous solution inactivates several enzymes--alanine aminotransferase, alkaline phosphatase , Na+/K(+)-ATPase, creatine kinase and glutamine synthetase--but not isocitrate dehydrogenase and malate dehydrogenase.”
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