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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Alkaline Phosphatase
supplement:
Tryptophan
Research Papers that Mention the Interaction
“ l-Tryptophan , but not d-tryptophan, inhibits human placental and intestinal alkaline phosphatases , but not those of liver and bone.”
L-tryptophan. A non-allosteric organ-specific uncompetitive inhibitor of human placental alkaline phosphatase.“The enzyme kinetics indicate that dl-tryptophan possesses chiral discrimination inhibition and l-tryptophan exhibits uncompetitive inhibition for ALP , compared with no obvious inhibition observed with its enantiomer.”
Magnetic nanoparticles coated with immobilized alkaline phosphatase for enzymolysis and enzyme inhibition assays.“These studies suggest that the active site residues His and Trp at the E. coli enzyme positions 153 and 328, respectively, at least partially dictate the metal specificity of alkaline phosphatase.”
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