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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Alkaline Phosphatase
supplement:
Thiamine Pyrophosphate
Research Papers that Mention the Interaction
“… alkaline phosphatase … TPP from 20 to 84 μM and for pyruvate from 2.3 to 4.6 mM, while the V(max) changed from 0.806 …⁻¹. These results suggest that the Pdc1p phosphorylation dependent on SIT4 occurs at residues that change the apparent affinity for TPP and pyruvate.”
Pyruvate decarboxylase activity is regulated by the Ser/Thr protein phosphatase Sit4p in the yeast Saccharomyces cerevisiae.
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