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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Alkaline Phosphatase
supplement:
Tannins
Research Papers that Mention the Interaction
“The various gallotannin preparations bound differently to ALP and influenced the size of aggregates of ALP , which may be related to ability to promote mineralization.”
Enhancement of Biomimetic Enzymatic Mineralization of Gellan Gum Polysaccharide Hydrogels by Plant-Derived Gallotannins“In vivo and in vitro exposure of saponin (active component of S. mukorossi pericarp) and tannic acid (active component of T. chebula) significantly inhibited the AChE, ACP and ALP activity in the nervous tissue of L. acuminata.”
Inhibition kinetics of certain enzymes in the nervous tissue of vector snail Lymnaea acuminata by active molluscicidal components of Sapindus mukorossi and Terminalia chebula.“Using in vitro experiments on purified brush border membranes, AP activity was found to be inhibited by grape tannins ; this inhibition was prevented by the detergent Triton X-100.”
“This shows that the formation of covalent bonds between alkaline phosphatase and tannic acid is deleterious for its conformation and activity.”
Multilayered films made from tannic acid and alkaline phosphatasewith enzymatic activity and electrochemical behavior.
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