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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Alkaline Phosphatase and Tannins

Research Papers that Mention the Interaction

The various gallotannin preparations bound differently to ALP and influenced the size of aggregates of ALP , which may be related to ability to promote mineralization.
International journal of molecular sciences  •  2020  |  View Paper
In vivo and in vitro exposure of saponin (active component of S. mukorossi pericarp) and tannic acid (active component of T. chebula) significantly inhibited the AChE, ACP and ALP activity in the nervous tissue of L. acuminata.
Chemosphere  •  2011  |  View Paper
Using in vitro experiments on purified brush border membranes, AP activity was found to be inhibited by grape tannins ; this inhibition was prevented by the detergent Triton X-100.
Enzyme & protein  •  1994  |  View Paper
This shows that the formation of covalent bonds between alkaline phosphatase and tannic acid is deleterious for its conformation and activity.
Journal of colloid and interface science  •  2018  |  View Paper