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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Alkaline Phosphatase
supplement:
Silymarin
Research Papers that Mention the Interaction
“The standard drug, silymarin produced significant (P<0.001) decrease in AST, ALT, ALP , LDH, TB, TG and cholesterol and increase in TP.”
The Protective Action of the Aqueous Extract of Auricularia polytricha in Paracetamol Induced Hepatotoxicity in Rats.“It was found that silymarin stimulated alkaline phosphatase ( ALP ) activity and calcium nodule formation in a dose-dependent manner with a substantial effect on osteoblast proliferation.”
“ SMN in preventive and protective forms significantly (p<0.05) improved the DOX-induced weight loss and lowered the alkaline phosphatase level.”
“ Silymarin also stabilized cellular membrane structure and regulated the levels of AST, ALT, ALP , CK, and LDH activity.”
“ Silymarin treatment reduced the levels of ALT, AST, and ALP by 56.1-62.8, 56.0-64.0, and 50.1-58.2%, respectively.”
“Meanwhile, silymarin reduced ALT, AST and ALP levels by 62.7%, 66.1% and 65.1% respectively.”
“Meanwhile, silymarin alone reduced ALT, AST and ALP levels by 65.9, 52 and 62.3%, respectively.”
“Moreover, silymarin significantly decreased the elevation of aspartate aminotransferase (AST), alanine aminotransferase, and alkaline phosphatase in serum, and also reversed the altered expressions of α‐smooth muscle actin in liver tissue.”
“Meanwhile, silymarin reduced elevated ALT, AST and ALP levels by 53.1, 26.9 and 66%, respectively.”
“ Silymarin by itself increased AP membrane activity.”
“ Silymarin cotreatment prevented the AP (completely) and the GGTP (partially) falls caused by CCI4.”
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