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Last Updated: 2 years ago

Possible Interaction: Alkaline Phosphatase and Silymarin

Research Papers that Mention the Interaction

The standard drug, silymarin produced significant (P<0.001) decrease in AST, ALT, ALP , LDH, TB, TG and cholesterol and increase in TP.
Recent patents on drug delivery & formulation  •  2016  |  View Paper
It was found that silymarin stimulated alkaline phosphatase ( ALP ) activity and calcium nodule formation in a dose-dependent manner with a substantial effect on osteoblast proliferation.
Experimental biology and medicine  •  2012  |  View Paper
SMN in preventive and protective forms significantly (p<0.05) improved the DOX-induced weight loss and lowered the alkaline phosphatase level.
Phytomedicine : international journal of phytotherapy and phytopharmacology  •  2012  |  View Paper
Silymarin also stabilized cellular membrane structure and regulated the levels of AST, ALT, ALP , CK, and LDH activity.
Fish Physiology and Biochemistry  •  2011  |  View Paper
Silymarin treatment reduced the levels of ALT, AST, and ALP by 56.1-62.8, 56.0-64.0, and 50.1-58.2%, respectively.
Drug discoveries & therapeutics  •  2010  |  View Paper
Meanwhile, silymarin reduced ALT, AST and ALP levels by 62.7%, 66.1% and 65.1% respectively.
Fundamental & clinical pharmacology  •  2009  |  View Paper
Meanwhile, silymarin alone reduced ALT, AST and ALP levels by 65.9, 52 and 62.3%, respectively.
Inflammopharmacology  •  2009  |  View Paper
Moreover, silymarin significantly decreased the elevation of aspartate aminotransferase (AST), alanine aminotransferase, and alkaline phosphatase in serum, and also reversed the altered expressions of α‐smooth muscle actin in liver tissue.
Journal of viral hepatitis  •  2008  |  View Paper
Meanwhile, silymarin reduced elevated ALT, AST and ALP levels by 53.1, 26.9 and 66%, respectively.
Acta biologica Hungarica  •  2007  |  View Paper
Silymarin by itself increased AP membrane activity.
Silymarin cotreatment prevented the AP (completely) and the GGTP (partially) falls caused by CCI4.
Journal of applied toxicology : JAT  •  1990  |  View Paper
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