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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Alkaline Phosphatase and Serine

Research Papers that Mention the Interaction

Exposure to D‐Ser not only suppressed several chondrocytic maturation markers, including alkaline phosphatase (ALP) activity, Ca2+ accumulation, nodule formation, and osteopontin expression, in rat chondrocytes, but also delayed chondral mineralization in mouse metatarsals.
Journal of cellular physiology  •  2009  |  View Paper
In vitro, SER significantly reduced osteogenic differentiation and mineralization of rat calvarial cells with concomitant reduction of osteoblast marker genes including alkaline phosphatase (Alpl), osterix (Sp7), and osteocalcin (Bglap).
Journal of periodontology  •  2016  |  View Paper
7.2.14 binding is abolished when the molecule is phosphorylated, presumably at a serine residue in exon 7, whereas treatment of material in cell lysates with alkaline phosphatase increases the intensity of the binding.
Journal of immunology  •  1993  |  View Paper