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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Alkaline Phosphatase
supplement:
Rutin
Research Papers that Mention the Interaction
“Moreover, rutin upregulated ALP activity and enhanced the number of mineralized nodules.”
Effects of rutin on the oxidative stress, proliferation and osteogenic differentiation of periodontal ligament stem cells in LPS-induced inflammatory environment and the underlying mechanism“Here, our findings showed that rutin enhanced PDLSCs proliferation, increased ALP activity, and matrix mineralization.”
“RT-PCR and Western blot results showed that rutin could enhance the expression of osteogenic genes and proteins such as COL1, ALP , and RUNX2 under inflammatory state.”
“When examining the influence of rutin on vitamin D levels and the activity of alkaline phosphatase enzyme, it was found to enhance both, while decreasing acid phosphatase which is a marker of osteoporosis.”
“Quercetin and rutin also increased alkaline phosphatase activity by about 150 and 240% and demonstrated mineralization up to 110 and 200% respectively as compared to control (which was considered as 100%).”
Assessment of the role of flavonoids for inducing osteoblast differentiation in isolated mouse bone marrow derived mesenchymal stem cells.“ Rutin alone also increased the activity of ALP (to 154.4±12.2%), the expression of collagen type I (to 126.6±6.2%), and the degree of mineralization (to 112.3±5.0%).”
Effects of Watercress Containing Rutin and Rutin Alone on the Proliferation and Osteogenic Differentiation of Human Osteoblast-like MG-63 Cells
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