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Discover Supplement-Drug Interactions
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Last Updated: 4 years ago
drug:
Alkaline Phosphatase
supplement:
Oxytocin
Research Papers that Mention the Interaction
“Furthermore, 50 nM OT significantly up-regulated expression of osteogenesis-related genes-alkaline phosphatase ( ALP ), Collagen I (Col I), runt related transcription factor 2 (Runx 2), osteopontin (OPN) and osteocalcin (OCN)-at specific time points compared with osteogenic inductive medium (p < 0.05).”
“In addition, … 50 nM OT … ALP , Col I, and Runx 2 at day 7 and day 14 (p < 0.01), as well as activating the phosphorylation of extracellular-… protein kinase B (AKT) pathway; notably, 50 nM OT inhibited phosphorylation of the phosphatidylinositol 3-kinase (PI3K) pathway (p < 0.05).”
Oxytocin facilitates the proliferation, migration and osteogenic differentiation of human periodontal stem cells in vitro.
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