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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Alkaline Phosphatase and Myricetin

Research Papers that Mention the Interaction

Myricetin significantly increased cell proliferation, alkaline phosphatase (ALP) activity, and alizarin red‐mineralization activity in hPDLSCs in a dose‐dependent manner.
These results demonstrate that myricetin promoted osteogenic differentiation by the up‐regulation of ALP activity and expression of osteogenic‐related factors through BMP‐2/Smad and ERK/JNK/p38 MAPK pathways.
European journal of pharmacology  •  2018  |  View Paper
Myricetin increased the mRNA expressions of Osteocalcin (OCN), Collagen type I (COL-I), ALP and Runt-related transcription factor 2 (RUNX2).
We found that the ALP activity and the mineralization of hBMSCs were enhanced by treatment with myricetin.
European journal of pharmacology  •  2014  |  View Paper
The … myricetin increased body weight gain and …‐induced reduction in BMD, enhanced alkaline phosphatase (ALP) activity, and upregulated osteocalcin (OCN), bone morphogenetic protein 2 (BMP2) and runt‐related transcription factor 2 (Runx2) … reduced tartrate‐resistant acid phosphatase (TRAP) activity and C‐terminal telopeptide of type I collagen (CTx) level.
Life sciences  •  2018  |  View Paper