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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Alkaline Phosphatase
supplement:
Methylselenocysteine
Research Papers that Mention the Interaction
“Osteogenic stimulation of MSC significantly increased their metabolic activity whereas collagen-1α and alkaline phosphatase gene expressions declined.”
Human Endothelial-Like Differentiated Precursor Cells Maintain Their Endothelial Characteristics When Cocultured with Mesenchymal Stem Cell and Seeded onto Human Cancellous Bone“ MSC cultured in osteogenic medium increased expression of osteonectin, Runt-related transcription factor 2 (RUNX-2), osteocalcin, and alkaline phosphatase.”
“An in vitro osteogenic assay was used … that NE can inhibit the formation of MSC bone nodules and expression of … marker genes alkaline phosphatase ( ALP ), osteocalcin (OCN), and runt-related transcription factor-2 (RUNX2), but knockdown of … by siRNA can abolish such inhibition of the osteogenic differentiation of MSCs.”
Sympathetic Denervation-Induced MSC Mobilization in Distraction Osteogenesis Associates with Inhibition of MSC Migration and Osteogenesis by Norepinephrine/adrb3
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