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Last Updated: 3 years ago

Possible Interaction: Alkaline Phosphatase and Magnesium

Research Papers that Mention the Interaction

We hypothesize that oxidative stress in AlP poisoning buffered the magnesium leading to a transient fall in magnesium and magnesium dependent GSH, resulting in increased susceptibility of oxygen free radical injury and accelerated lipid peroxidation.
Magnesium research  •  1997  |  View Paper
Early osteogenic marker … including osterix, alkaline phosphatase , and type I collagen were significantly … in MSCs under high concentration of magnesium , whereas late marker genes such as osteopontin, osteocalcin, and bone morphogenetic protein 2 were upregulated … statistical significance compared with those in normal differentiation medium containing 0.8 mM magnesium.
Stem Cell Research & Therapy  •  2017  |  View Paper
Magnesium exposure profoundly enhanced alkaline phosphatase (ALP) gene expression and activity even at a relatively low magnesium concentration (2.5 mm).
Journal of tissue engineering and regenerative medicine  •  2016  |  View Paper
We found that high concentrations of magnesium markedly inhibited the deposition of mineral matrix by SaOS-2 as well as the activity of alkaline phosphatase , a marker of osteoblast differentiation.
Magnesium research  •  2011  |  View Paper
In the presence of magnesium , the dissociation rates of the complexes with C·AP andSMeG·AP are increased more than 20-fold, allowing each thymine DNA glycosylase to remove more than one uracil or thymine from C·U and SMeG·T mismatches in DNA.
The Journal of Biological Chemistry  •  1999  |  View Paper
Nevertheless, the influence of magnesium and calcium ions on the ATPase activity of alkaline phosphatase means that precautions must be taken when assaying for Ca2+-ATPase in the presence of alkaline phosphatase.
Canadian journal of biochemistry  •  1979  |  View Paper
Metal ions other than zinc and magnesium were effective in modulating the activity of rat osseous plate alkaline phosphatase.
The International journal of biochemistry  •  1992  |  View Paper
High concentrations of magnesium caused a pronounced inhibition on the labelling of the alkaline phosphatase band but had no effect on the phosphorylation of other proteins.
The International journal of biochemistry  •  1988  |  View Paper
Thus, magnesium is influencing the expression of Cbfα1 and ALP associated with VC and may have the potential to serve as a role for VC in clinical situations.
Biomedical reports  •  2015  |  View Paper
In the HOS-58 cells, the AP activity was statistically significant (P < 0.05) higher at a supplement of 5–10 mg of silver than of Ti-6 Al-4V at the same doses.
Sarcoma  •  2007  |  View Paper
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