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Last Updated: 3 years ago

Possible Interaction: Alkaline Phosphatase and Magnesium Cation

Research Papers that Mention the Interaction

Magnesium ions induced significant (P<0.05) increases in cell viability, alkaline phosphate activity and osteocalcin levels of human osteoblasts.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas  •  2016  |  View Paper
The western blot results demonstrated that the introduction of Mg+ heightened the expressions of ALP and OCN.
Journal of Materials Science: Materials in Medicine  •  2019  |  View Paper
Alkaline phosphatase from diabetic rats had a better affinity (K0.5 = 38 microM) for magnesium ions than controls (K0.5 = 91 microM).
Comparative biochemistry and physiology. Comparative physiology  •  1993  |  View Paper
Binding of magnesium ions to alkaline phosphatase induces conformational changes which activate the enzyme.
The International journal of biochemistry  •  1990  |  View Paper
Magnesium ions stimulated the activities at optimum concentrations of 10 mM for acid phosphatase and 2mM for alkaline phosphatase.
Archives of oral biology  •  1978  |  View Paper
The alkaline phosphatase of the extracts was stimulated about 2.5-fold by the addition of 10−3m Mg++ or Zn++, whereas it was inhibited completely by 10−3 m ethylenediaminetetraacetic acid.
Japanese journal of microbiology  •  1972  |  View Paper
Mg+ + retarded thermal inactivation of alkaline phosphatase.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine  •  1966  |  View Paper