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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Alkaline Phosphatase and Ipriflavone

Research Papers that Mention the Interaction

Conclusion IP can promote the expression of ALP and Runx2 which was probably related to the GPR30-mediated PI3K/AKT signaling pathway.
Drug design, development and therapy  •  2018  |  View Paper
The alkaline phosphatase (ALP) activity, employed as a marker of bone cell differentiation, was significantly enhanced by IP in both cell types; however, the concentration at which IP had a maximal effect was lower in ROB cells than in HPLF (10−10 versus 10−7 M, respectively).
Calcified Tissue International  •  2005  |  View Paper
We show here that ipriflavone also promotes the deposition of calcium and the formation of mineralized nodules by newborn rat calvarial osteoblast-like (ROB) cells as well as the activity of alkaline phosphatase.
Journal of biochemistry  •  1999  |  View Paper