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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Alkaline Phosphatase
supplement:
Histidine
Research Papers that Mention the Interaction
“Incorporating glutamic acid, aspartic acid, or histidine proximal to lysine residues in histone N‐terminal tails increases AP reactivity as much as sixfold.”
Histone Tail Sequences Balance Their Role in Genetic Regulation and the Need To Protect DNA against Destruction in Nucleosome Core Particles Containing Abasic Sites“ Histidine inhibited ALP activity and adipogenesis in human preadipocytes and 3T3-L1 cells.”
“ Histidine inhibited adipogenesis and alkaline phosphatase to a greater extent than did levamisole, but Phe-Gly-Gly had no effect on these variables.”
Alkaline phosphatase is involved in the control of adipogenesis in the murine preadipocyte cell line, 3T3-L1.“ Alkaline phosphatase was effectively inhibited by EDTA, Zn2+, histidine and urea therefore resembling the inhibition characteristics of alkaline phosphatase in the placenta and kidney, but not that in the liver and intestine, which differed markedly.”
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