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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Alkaline Phosphatase and Hesperetin

Research Papers that Mention the Interaction

Hesperetin significantly increased ALP activity at doses of 1, 10, and 100 µM. Pretreatment of cells with hesperetin alleviated the high-glucose-induced suppression of the osteogenic activity of PDLSCs.
PloS one  •  2013  |  View Paper
Hesperetin (10−7–10−5 M) caused a significant elevation of alkaline phosphatase (ALP) activity, collagen content, and total antioxidant potential of MC3T3-E1 cells in the presence of 20 mM dRib (p < 0.05).
Cell Biology and Toxicology  •  2007  |  View Paper
Our results showed that hesperetin promoted alkaline phosphatase (ALP) activity and the mineralization in DEX-treated BMSCs during osteogenic differentiation.
Medical Molecular Morphology  •  2020  |  View Paper