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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Alkaline Phosphatase
supplement:
Gossypol
Research Papers that Mention the Interaction
“ Gossypol also causes a significant reduction in the activities of sucrase, lactase, maltase and alkaline phosphatase in the intestinal homogenates as well as in the purified brush border membrane of the microvillus.”
Reversibility of the effects of Gossypol acetic acid, an antispermatogenic/antifertility agent on the intestinal structure and functions of male albino rats“ Gossypol also caused significant decrease in the intestinal brush border membrane--associated enzymes, sucrase, lactase, maltase and alkaline phosphatase.”
“At a concentration of 6 mg per gm mucosa, gossypol inhibited the activities of alkaline phosphatase , maltase, and sucrase by 57, 73, and 77%, respectively.”
Inactivation of intestinal brush-border enzymes by gossypol.
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