Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago

Possible Interaction: Alkaline Phosphatase and Gamma-Aminobutyric Acid

Research Papers that Mention the Interaction

The results showed that GABA enhanced the intensity of ALP staining, ALP activity, and accumulation of Ca2+ mineralized nodules in hMSCs during osteogenic induction.
Current gene therapy  •  2020  |  View Paper
Moreover, acid phosphatase (ACP), alkaline phosphatase (AKP), aspartate aminotransferase (AST) and alanine aminotransferase (ALT) activities were significantly increased in the hepatopancreas by the GABA treatment.
General and comparative endocrinology  •  2020  |  View Paper
Sustained exposure to GABA significantly inhibited alkaline phosphatase (ALP) activity, but not cellular viability, at concentrations above 0.1 mM in osteoblasts cultured for 3 to 28 days.
European journal of pharmacology  •  2006  |  View Paper
3 NANC nerve‐mediated relaxations induced by adenosine 5′‐triphosphate (ATP), acetylcholine (ACh) and γ‐aminobutyric acid GABA ) were significantly enhanced by 4‐AP and charybdotoxin but not by apamin.
British journal of pharmacology  •  1993  |  View Paper
4 γ‐Aminobutyric acid‐activated Cl− currents were also reversibly inhibited by 1 to 10 μm AP.
British journal of pharmacology  •  1992  |  View Paper