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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Alkaline Phosphatase and Epinephrine

Research Papers that Mention the Interaction

Among various agents, epinephrine was recently found to increase ALP activity in differentiating MC3T3-E1 cells by stimulating alpha1 adrenergic receptors coupled to Gi proteins.
Endocrinology  •  1999  |  View Paper
In addition to its effect on cell replication, epinephrine also enhanced alkaline phosphatase (ALP) activity in these cells but had little effect on collagen synthesis and osteocalcin production.
Bone  •  1998  |  View Paper
Abstract Alkaline phosphatases of serum, bone, intestinal mucosa, and milk, in glycine buffer, are inhibited to the extent of 70–100% by adrenaline , adernochrome, and other o -dihydroxyphenols with substitution at C-4, and by other o -quionones, at concentrations of 0.2−0.5 m M .
Biochimica et biophysica acta  •  1961  |  View Paper