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Last Updated: 3 years ago

Possible Interaction: Alkaline Phosphatase and Cysteine

Research Papers that Mention the Interaction

Cysteine increased the ALP activity and the phosphorylation of extracellular signal-regulated kinase.
Cysteine increased the levels of alkaline phosphatase ( ALP ) and 17β-estradiol in the serum of the OVX mice and improved the bone mineral density in the OVX mice.
Reproductive Sciences  •  2016  |  View Paper
Like kidney ALP, this ALP was markedly inhibited by 0.5 mmol/l L-cysteine.
Enzyme & protein  •  1996  |  View Paper
Thus, there are two sites on human liver and placental alkaline phosphatase that interact with L-cysteine ; a Mg2+-binding site, which results in activation, and a site that involves one or both of the bound Zn2+ ions and results in inactivation.
Biochimica et biophysica acta  •  1986  |  View Paper
Decreased inhibitory effect by cysteine and cyanide on alkaline phosphatase has been observed in the later passages.
Experimental cell research  •  1970  |  View Paper
The results indicate that cysteine inhibits alkaline phosphatase by chelation of the Zn atom at the active site of the enzyme.
Biochimica et biophysica acta  •  1966  |  View Paper
Cysteine or levamisole was used to inhibit alkaline phosphatase activity.
Journal of applied physiology  •  1986  |  View Paper
The chondrocytic alkaline phosphatase is inhibited irreversibly by Be2+, EDTA, EGTA, ethane-1-hydroxydiphosphonate, dichloromethane diphosphonate, L-cysteine , phenyl-methylsulfonyl fluoride, N-ethylmaleimide and iodoacetamide.
Biochimica et biophysica acta  •  1979  |  View Paper
The mitochondrial extracts contained alkaline phosphatase activity that was inhibited by L-cysteine and dithiothreitol.
Biochemical and biophysical research communications  •  1978  |  View Paper
Cysteine (0.1 mM) altered the D37 of both AP and ATPase to 21 and 87 krads, respectively, whereas 4A1N (0.1 mM) changed the D37 of AP to 180 and ATPase to 148 krads.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine  •  1968  |  View Paper
The results prove that acid phosphatase plays an important part in keratinization and that the earlier reports of absence of alkaline phosphatase in squamous epithelium were due to the inhibitory effect of cysteine.
Acta oto-laryngologica  •  1973  |  View Paper