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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Alkaline Phosphatase
supplement:
Cupric Cation
Research Papers that Mention the Interaction
“ ALP catalyzes the hydrolysis of PPi, causing the release of Cu(II).”
Colorimetric determination of the activity of alkaline phosphatase based on the use of Cu(II)-modulated G-quadruplex-based DNAzymes“ Cupric ions inhibited alkaline phosphatase activity at all phases of the cycle.”
“ Alkaline phosphatase (APase) was greater than 99% inactivated upon incubation with myo-inositol hexakisphosphate (IHP) and Cu(II) ions.”
“Reactions of APase with IHP plus Cu(II) were competitively inhibited by zinc ions.”
Inactivation of intestinal alkaline phosphatase by inositol hexaphosphate-Cu (II) coordinate complexes.“Although all of the hydrazones but one … evaluated alone, the concurrent injection of cupric ion increased … an avoli alkaline phosphatase was found to be inhibited by two thiosemicarbazones in a manner similar to that previously … these agents against alkaline phosphatase derived from Sarcoma 180-6-thiopurine resistant ascites cells.”
“ Cu(II ) also decreased sucrose consumption, ATP content and alkaline phosphatase activity of the biofilm.”
Dominance of sphingomonads in a copper-exposed biofilm community for groundwater treatment.
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