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Last Updated: 2 years ago

Possible Interaction: Alkaline Phosphatase and Cupric Cation

Research Papers that Mention the Interaction

ALP catalyzes the hydrolysis of PPi, causing the release of Cu(II).
Microchimica Acta  •  2018  |  View Paper
Cupric ions inhibited alkaline phosphatase activity at all phases of the cycle.
The Journal of obstetrics and gynaecology of the British Commonwealth  •  1973  |  View Paper
Alkaline phosphatase (APase) was greater than 99% inactivated upon incubation with myo-inositol hexakisphosphate (IHP) and Cu(II) ions.
Reactions of APase with IHP plus Cu(II) were competitively inhibited by zinc ions.
Journal of inorganic biochemistry  •  1991  |  View Paper
Although all of the hydrazones but one … evaluated alone, the concurrent injection of cupric ion increased … an avoli alkaline phosphatase was found to be inhibited by two thiosemicarbazones in a manner similar to that previously … these agents against alkaline phosphatase derived from Sarcoma 180-6-thiopurine resistant ascites cells.
Journal of medicinal chemistry  •  1976  |  View Paper
Cu(II ) also decreased sucrose consumption, ATP content and alkaline phosphatase activity of the biofilm.
Microbiology  •  2007  |  View Paper