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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Alkaline Phosphatase and Chondroitin Sulfates

Research Papers that Mention the Interaction

CS and HA significantly suppressed ALP activity without affecting ATDC5 cell proliferation.
In conclusion, supplemented CS directly inhibits ALP to prevent the progression of chondrocytes from differentiation to mineralization.
The suppressive effect of CS on ALP activity was abrogated by pre-treatment with chondroitinase ABC (CSase).
Biological & pharmaceutical bulletin  •  2017  |  View Paper
On days 1, 7 and 14 a significantly higher activity of alkaline phosphatase , an early marker of osteogenesis, was detected around CS modified cements in both types of media.
Materials science & engineering. C, Materials for biological applications  •  2012  |  View Paper